The man, in his 20s, stabbed six passers-by, including a middle school student, in Kashgar around 8.05 p.m., police said Tuesday.
Kashgar, an ancient oasis city on the northern Silk Road, close to Tajikistan in China's Xinjiang Uyghur autonomous region, has a population of 350,000.
The police surrounded him and fired warning shots. The man resisted arrest and committed suicide by cutting his throat with a knife three times, said Xinhua.
Five bottles, suspected to contain marijuana, were found in the man's pocket.
All the six injured were taken to hospital, where the condition of the student was said to be serious.
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